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. 2013 Mar 6;8(3):e58426. doi: 10.1371/journal.pone.0058426

Figure 4. AMD3465 reduces tumor metastases in a syngenic breast cancer model.

Figure 4

The size/number (indicated by arrows) of metastatic nodules in the 4T1 tumor bearing mice treated with PBS (control) or AMD3465 in both the lung and liver as determined by H&E staining. We also confirmed the metastatic nodules were GFP positive as were the primary tumors. A detailed treatment procedure for the metastasis assay is described in the Method section.