Figure 2.
Representative structures of Arginine (stick figure) bound to Arginase I with (left panel) and without (right panel) hydroxide ion (atom colored CPK). The Mg2+ ions are shown as green vdW spheres. Images created using Discovery Studio 3.0 (Accelrys Inc). Structures were obtained following modeling of substrate arginine based on the aminohistidine analogue inhibitor Z70 (PDB: 3MFV).