Table 3.

Results from Figs. 3 and 4 are summarized to highlight the differences between the effects of LPS and PAN on TLRs, MyD88, NF-kB, IRF and TRIF at 1 and 6 h

	A	B	C	D
Time	LPS/Control ≥3-fold	PAN/Control ≥3-fold	LPS/PAN ≥3-fold	LPS/PAN <3-fold
1 h	TLR 1 > 4 ≥ 2 > 3 > 6 > 5	TLR-4, 5	TLR-1, 2, 3, 4 and 6	TLR-5
	MyD88, NF-κB		MYD88, NF-κB	IRF3, TRIF
6 h	TLR 1 > 6 > 2 ≥ 4 > 3 ≈ 5	TLR-3, 5	TLR-1, 2, 4 and 6	TLR-5 and 3
	MyD88, NF-κB		MYD88, NF-κB	IRF3, TRIF

Columns A and B: LPS caused greater upregulation of TLR-1 than of other subtypes at both 1 and 6 h. PAN consistently upregulated TLR-5 at both time points. LPS upregulated the expression of MyD88 and NF-κB but PAN did not. TLR-5 was least affected by LPS but most affected by PAN at both time points

Columns C and D: Expression of TLR-5 was comparable in LPS and PAN treated cell at both 1 and 6 h