Table 2.
Demographics and clinical characteristics of the PTCL: LAHS group versus the non-LAHS group
LAHS group (n = 36) | Non-LAHS group (n = 123) | P value | |
---|---|---|---|
Median age (years) | 48 | 46 | |
Range | 16–78 | 10–77 | |
Male/female | 23/13 | 86/37 | |
III/IV stage | 34 (94 %) | 93 (76 %) | 0.013 |
IPI | |||
0–1 | 4 (11 %) | 30 (24 %) | 0.087 |
2–3 | 22 (61 %) | 79 (64 %) | 0.733 |
4–5 | 10 (28 %) | 14 (11 %) | 0.694 |
B symptoms | 36 (100 %) | 94 (76 %) | 0.001 |
Fever | 33 (92 %) | 51 (42 %) | <0.001 |
Hepatosplenomegaly | 26 (72 %) | 28 (23 %) | <0.001 |
Cytopenia for at least two cell linesa | 28 (78 %) | 16 (13 %) | <0.001 |
With BMI | 20 (56 %) | 34 (28 %) | 0.002 |
PTCL-NOS | 28 (78 %) | 64 (52 %) | |
SCPTCL | 2 (6 %) | 5 (4 %) | |
AILT | 3 (8 %) | 18 (15 %) | |
NKTCL | 3 (8 %) | 24 (20 %) | |
ETTL | 0 | 4 (3 %) | |
ALCL | 0 | 4 (3 %) |
B symptoms fever, night sweats, or weight loss, IPI international prognostic index, BMI bone marrow involvement, PTCL-NOS peripheral T cell lymphoma, not otherwise specified, SCPTCL subcutaneous panniculitis-like T cell lymphoma, AILT angioimmunoblastic T cell lymphoma, NKTCL nasal NK/T cell lymphoma, ETTL enteropathic type T cell lymphoma, ALCL anaplastic large cell lymphoma
aCytopenia for at least two cell lines with hemoglobin <90 g/L (or below 120 g/L for more than 4 weeks), platelet <10.0 × 109/L, and neutrophils <1.0 × 109/L