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A–D, Serum T (A), DHT (B), E2 (C), and 17-OHP (D) at baseline, 48 hours after acyline administration (day 3), and 1 week after oral medication administration (day 10) by treatment group. Dashed lines represent the normal reference range. Ana, anastrazole 1 mg; Dut, dutasteride 2.5 mg; K400, ketoconazole 400 mg; K800, ketoconazole 800 mg; Pla, placebo. *P < .05 compared with baseline; **P < .05 compared with all other treatment groups at day 10.
