Figure 1.

A, The schematic presentation showed the positions of 24 tagSNPs (with SNP identifications) that spanned the PPARG genomic region. B, Sliding-window (3 SNP) haplotype-based analysis of 24 PPARG tagSNPs using additive genetic model in combined multiethnic WHI-OS case-control sample. The haplotype effects were estimated using an omnibus likelihood ratio test. The x-axis denoted the sliding window frames, and the y-axis denoted the −log10(P value). A −log10(P value) greater than 2.64 was used as the global significance threshold using Bonferroni correction for the 22 window frames, and none met the criterion.