Figure 8. Representative structure of Et-KuQ docked on the CPT+Top1+DNA ternary complex.

The Et-KuQ is represented in cyan; the lateral chains of the residues of the catalytic pentad and the CPT are represented as sticks and labelled; the rest of the protein appears as a ribbon; the base-pairs in position +1 and −1 as black lines. A blue dashed line indicates the distance between the 5′ DNA end, represented as a red sphere, and the closest Et-KuQ oxygen acceptor.