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. 2013 Feb 20;10(4):377–381. doi: 10.7150/ijms.5224

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Effect of curcumin (Cur) treatment on the pain threshold in diabetic rats. Diabetes mellitus (DM) was associated with decreases in mechanical paw withdrawal threshold (A) and thermal paw withdrawal latency (B), but the decreases were significantly less in the curcumin-treated diabetic group than in the vehicle-treated diabetic group. Data are expressed as mean ± S.E.M. (n = 12 per group). BL, baseline; Con, control *p = 0.01 vs. control group; ** p = 0.03 vs. DM group; ^# p = 0.01 vs. control group; ^## p = 0.04 vs. DM group.