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. 2013 Feb 21;10(4):399–407. doi: 10.7150/ijms.5407

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Double immunofluorescence staining showed up-regulation of markers of stem cells (OCT-4, SOX-2) and down-regulation of GFAP in U87 cells. A-D: U87 cells in control group; E-L: U87 cells after hypoxic treatment for 48 h.