Table 4.
Disproportionality analysis for duloxetine and pregnancy cases identified in the AERS database.
| Group indicating: | Number of cases | EB05 | |
|---|---|---|---|
| Duloxetine | Other drugs | ||
| Full AERS background | |||
| Congenital anomaly | 89 | 42,520 | 0.69 |
| Spontaneous Abortion | 66 | 12,469 | 0.55 |
| Induced Abortion | 11 | 4,620 | 0.20 |
| Ectopic Pregnancy | 4 | 1,603 | 0.14 |
| Still Birth | 6 | 3,973 | 0.15 |
| Customized antidepressant background | |||
| Congenital anomaly | 89 | 6,028 | 0.21 |
| Spontaneous Abortion | 66 | 862 | 0.60 |
| Induced Abortion | 11 | 358 | 0.28 |
| Ectopic Pregnancy | 4 | 66 | 0.31 |
| Still Birth | 6 | 351 | 0.17 |
EB05 = the lower bound of 90% confidence interval of empirical Bayes geometric mean.