Table 3. The results of the univariate and multivariate analyses for overall survival.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
|
Variable |
Hazard ratio |
P-value |
Hazard ratio |
P-value |
|
YB-1 nuclear expression | ||||
| Negative | 0.1860 | 0.0090 | 0.1946 | 0.0420 |
| Positive |
1 |
|
1 |
|
|
Cyclin D1 | ||||
| <10% | 0.9242 | 0.8844 | 0.4718 | 0.2473 |
| ⩾10% |
1 |
|
1 |
|
|
Cyclin A | ||||
| <40% | 0.3077 | 0.0483 | 0.4814 | 0.4134 |
| ⩾40% |
1 |
|
1 |
|
|
Tumour location | ||||
| Extremities | 0.6057 | 0.5385 | 0.8155 | 0.8342 |
| Trunk |
1 |
|
1 |
|
|
Age, years | ||||
| <16 | 0.7271 | 0.6794 | 0.9583 | 0.8080 |
| ⩾16 |
1 |
|
1 |
|
|
MIB-1 | ||||
| <10% | 2.6766 | 0.1511 | 0.3813 | 0.2020 |
| ⩾10% | 1 | 1 | ||
Abbreviation: MIB-1=an antibody against ki-67; YB-1=Y-box binding protein-1.