Table 1. Patients diagnosed with colorectal cancer in two European countries between 1997 and 2004 (N=40 613).
Calvados(N=2481) | Côte d'Or(N=2329) | Saone et Loire(N=3081) | England (NYCRIS)(N=32722) | ||||||
---|---|---|---|---|---|---|---|---|---|
Variables |
N |
% |
N |
% |
N |
% |
N |
% |
P-values |
Sex |
|
|
|
|
|
|
|
|
0.402 |
Men | 1359 | 54.8 | 1300 | 55.8 | 1683 | 54.6 | 18 176 | 55.5 | |
Women |
1122 |
45.2 |
1029 |
44.2 |
1398 |
45.4 |
14 546 |
44.5 |
|
Age |
|
|
|
|
|
|
|
|
0.001 |
<61 | 523 | 21.1 | 482 | 20.7 | 508 | 16.5 | 5865 | 17.9 | |
61–69 | 475 | 19.1 | 452 | 19.4 | 672 | 21.8 | 7200 | 22.0 | |
70–79 | 712 | 28.7 | 641 | 27.5 | 893 | 29.0 | 9418 | 28.8 | |
⩾79 |
771 |
31.1 |
754 |
32.4 |
1008 |
32.7 |
10 239 |
31.3 |
|
Topography |
|
|
|
|
|
|
|
|
<0.001 |
Right colon | 765 | 30.8 | 740 | 31.8 | 1024 | 33.2 | 8881 | 27.1 | |
Left colon | 715 | 28.8 | 717 | 30.8 | 923 | 30.0 | 7917 | 24.2 | |
Unknown colona | 65 | 2.6 | 18 | 0.8 | 7 | 0.2 | 2879 | 8.8 | |
Rectosigmoid junction | 235 | 9.5 | 355 | 15.2 | 326 | 10.6 | 3269 | 10.0 | |
Rectum |
701 |
28.3 |
499 |
21.4 |
801 |
26.0 |
9776 |
29.9 |
|
Duke's stage |
|
|
|
|
|
|
|
|
<0.001 |
A | 390 | 15.7 | 409 | 17.6 | 567 | 18.4 | 3724 | 11.4 | |
B | 676 | 27.2 | 713 | 30.6 | 872 | 28.3 | 8567 | 26.2 | |
C | 592 | 23.9 | 477 | 20.5 | 657 | 21.3 | 7686 | 23.5 | |
‘D' | 644 | 26.0 | 543 | 23.3 | 743 | 24.1 | 7234 | 22.1 | |
Unstaged |
179 |
7.2 |
187 |
8.0 |
242 |
7.9 |
5511 |
16.8 |
|
Year of diagnosis |
|
|
|
|
|
|
|
|
0.007 |
1997 | 287 | 11.6 | 267 | 11.5 | 393 | 12.8 | 3782 | 11.6 | |
1998 | 305 | 12.3 | 258 | 11.1 | 389 | 12.6 | 4079 | 12.5 | |
1999 | 300 | 12.1 | 287 | 12.3 | 351 | 11.4 | 4143 | 12.7 | |
2000 | 308 | 12.4 | 280 | 12.0 | 418 | 13.6 | 4185 | 12.8 | |
2001 | 304 | 12.3 | 267 | 11.5 | 374 | 12.1 | 4069 | 12.4 | |
2002 | 299 | 12.1 | 296 | 12.7 | 356 | 11.6 | 4191 | 12.8 | |
2003 | 345 | 13.9 | 324 | 13.9 | 416 | 13.5 | 4096 | 12.5 | |
2004 |
333 |
13.4 |
350 |
15.0 |
384 |
12.5 |
4177 |
12.8 |
|
Surgical resection within 6 months since diagnosis |
|
|
|
|
|
|
|
|
<0.001 |
Yes | 2065 | 83.2 | 1944 | 83.5 | 2592 | 84.1 | 23 908 | 73.1 | |
No |
416 |
16.8 |
385 |
16.5 |
489 |
15.9 |
8814 |
26.9 |
|
Chemotherapy |
|
|
|
|
|
|
|
|
<0.001 |
Yes | 905 | 36.5 | 751 | 32.2 | 1069 | 34.7 | 8542 | 26.1 | |
No | 1559 | 62.8 | 1564 | 67.2 | 1982 | 64.3 | 24 180 | 73.9 | |
Unknown |
17 |
0.7 |
14 |
0.6 |
30 |
1.0 |
0 |
0.0 |
|
Radiotherapy |
|
|
|
|
|
|
|
|
<0.001 |
Yes | 375 | 15.1 | 374 | 16.1 | 586 | 19.0 | 4027 | 12.3 | |
No | 2095 | 84.4 | 1943 | 83.4 | 2467 | 80.1 | 28 695 | 87.7 | |
Unknown | 11 | 0.4 | 12 | 0.5 | 28 | 0.9 | 0 | 0.0 |
Abbreviation: NYCRIS=Northern and Yorkshire Cancer Registry Information Service.
Including C18.8.