Table 2. Cox's regression (CR) analysis.
| Response variable | Predictor variables | Hazards ratio | 95% Low | 95% High | P-value |
|---|---|---|---|---|---|
| Death |
PgR positive |
0.32 |
0.149 |
0.686 |
0.003 |
| |
p53 mutant |
2.61 |
1.266 |
5.383 |
0.009 |
| |
Lymph node positive |
2.782 |
1.239 |
6.249 |
0.013 |
| High SPF (⩾10) | 2.218 | 1.094 | 4.499 | 0.027 |
Abbreviations: PgR=progesterone receptor; SPF=S-phase fraction.
All variables were analysed by backwards step-wise Cox's proportional hazards regression model to find independent associations with survival. Independent associations were confirmed with PgR-positive status, p53 mutation, positive lymph nodes, and high S-phase fraction (SPF3).