Table 3. Backward stepwise Binary Logistic Regression (BLR) statistical analysis.
| Response variable | Predictor variables | β | P-value | OR (95% CI) |
|---|---|---|---|---|
| PgR |
p53 wild type |
0.72 |
0.030 |
2.05 (1.07–3.93) |
| |
Low DI tumours |
−0.67 |
0.030 |
0.51 (0.28–0.94) |
|
p53 wild type |
ER |
1.69 |
<0.001 |
5.40 (2.62–11.13) |
| |
Intermediate DI tumours |
−1.02 |
0.009 |
0.36 (0.17–0.78) |
| ER |
p53 wild type |
1.68 |
<0.001 |
5.37 (2.38–12.14) |
| |
HER2 |
1.20 |
0.013 |
3.34 (1.29–8.63) |
| HER2 |
ER |
1.38 |
0.002 |
3.96 (1.65–9.46) |
| |
High DI tumours |
−1.55 |
0.003 |
0.21 (0.08–0.59) |
| Low DI tumours |
PgR |
−0.76 |
0.012 |
0.47 (0.26–0.84) |
| Intermediate DI tumours |
p53 wild type |
−1.17 |
0.001 |
0.31 (0.15–0.63) |
| High DI tumours | HER2 | −1.42 | 0.004 | 0.24 (0.09–0.64) |
Abbreviations: CI=confidence interval; DI=DNA index; ER=oestrogen receptor; HER2=human epidermal growth factor receptor 2; OR=odds ratio; PgR=progesterone receptor.
Variables were analysed by backwards step-wise BLR. All significant associations between the predictor and response variables are shown and non-significant associations are omitted for brevity and clarity.