Table 1.
Baseline characteristics.
| Progesterone group (n=5) | Controls (n= 13) | |
|---|---|---|
| Tanner stage | 2.2 ± 0.8 (2, 1–3) | 2.2 ± 0.8 (2, 1–3) |
| Age (y) | 11.1 ± 1.5 (11.0, 9.2–13.0) | 11.0 ± 1.9(10.8, 7.4–13.5) |
| BMI (kg/m2) | 16.4 ± 1.4 (15.6, 15.1–18.3) | 18.4 ± 2.8 (17.2, 14.6–23.1) |
| BMI-for-age percentile | 31.6 ± 21.1 (34.0, 10.0–58.0) | 54.6 ± 30.8 (56.3, 5.1–92.8) |
| Estradiol (pg/ml) | 39.6 ± 9.4 (39.3, 26.6–50.0) | 38.0 ± 16.3(40.2, 5.1–68.2) |
| Total testosterone (ng/dl) | 9.3 ± 3.5 (11.0, 5.0–12.3) | 8.3 ± 5.5 (6.3, 5.0–23.5) |
| SHBG (nmol/liter) | 72.1 ± 20.4 (68.7, 52.1–103.0) | 55.3 ± 17.3 (51.0, 27.4–86.4) |
| Free testosterone (pmol/liter) | 3.4 ± 1.3 (3.0, 2.3–5.3) | 4.0 ± 2.9 (2.8, 1.2–11.0) |
| DHEAS (μg/dl) | 49.2 ± 29.5 (50.2, 12.7–79.0) | 52.6 ± 37.7 (45.9, 6.0–143.0) |
| Fasting insulin (μlU/ml) | 5.5 ± 3.5 (5.6, 1.3–9.7) | 10.9 ± 6.3 (10.8, 1.7–23.3) |
| Fasting glucose (mg/dl) | 85.2 ± 7.9 (88, 72–93) | 84.4 ± 4.4 (84, 79–91) |
Data are presented as mean ± SD (median, minimum–maximum).
BMI = body mass index; SHBG = sex hormone binding globulin; DHEAS = dehydroepiandrosterone sulfate. All comparisons (progesterone group vs. controls) were non-significant (p > 0.05), although there was a trend toward lower SHBG and higher insulin values in controls (p = 0.0619 and 0.0966, respectively). To convert from conventional to SI units: estradiol × 3.671 (pmol/liter); total testosterone × 0.0347 (nmol/liter); DHEAS × 27.21 (nmol/liter); insulin × 6.945 (pmol/liter); glucose × 0.0555 (mmol/liter).