Table 1.
The Results on the Simulated Mouse Chromosome 17 Under Different Sequencing Depth and Mutation Rates Between Duplicated Segments
| Mutation rate between duplicated segments | Depth of coverage | No. of predicted CNVs | No. of correct CNVs | False discovery rate | False negative rate |
|---|---|---|---|---|---|
| 1% | 30X | 102 | 100 | 2.0% | 0 |
| 15X | 102 | 100 | 2.0% | 0 | |
| 5X | 105 | 100 | 4.8% | 0 | |
| 0.5% | 30X | 102 | 100 | 2.0% | 0 |
| 15X | 105 | 100 | 4.8% | 0 | |
| 5X | 109 | 100 | 8.3% | 0 | |
| 0.1% | 30X | 101 | 97 | 4.0% | 3.0% |
| 15X | 107 | 98 | 8.4% | 2.0% | |
| 5X | 116 | 96 | 17.2% | 4.0% |
No. of predicated CNVs are the number of regions CNVeM reports as CNVs. False discovery rate is the ratio between number of false positives and number of predicted CNVs, while false negative rate is the ratio between number of false negatives and number of true CNVs.