Table 1. Definition of genomic alterations.

Genomic alterations	Definition		Description
SNP	Single-nucelotide polymorphism	Germiline	Inherited genetic variation in the DNA sequence that occurs when a single nucleotide is altered
CNV	Copy number variant	Germline	Inherited alteration of DNA that results in an abnormal number of copies of one or more segments of DNA (1 kilobase or larger)
SNV	Single-nucleotide variant	Somatic	Acquired genetic variation in the DNA sequence that occurs when a single nucleotide is altered (i.e., point mutation)
CNA	Copy number aberration	Somatic	Acquired alteration of DNA that results in an abnormal number of copies of one or more segments of DNA (1 kilobase or larger)