Table 2.
The maximal plasma concentration (C max), time to maximal plasma concentration (T max), areas under curve (AUC) and half-life (T 1/2) after steady administration of the medical food indicated for osteopenia/osteoporosis, the Squadrito study formulation, and the OTC bone supplement.
| Study parameters | Medical food | Squadrito study formulation | OTC bone supplement |
|---|---|---|---|
| T max (hrs) | 2 | 2 | 6 |
| C max (ng/mL ± StDev) | 188.4 ± 2.5 | 187.1 ± 3.5 | 153.3 ± 3.5 |
| AUC (ng·hr/mL) | 9221 ± 413 | 9818 ± 1370 | 6474 ± 287 |
| T 1/2 (hrs ± StDev) | 18.0 ± 6.9 | 20.9 ± 4.9 | 8.3 ± 1.9 |