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. 2013 Mar 7;9(3):e1003324. doi: 10.1371/journal.pgen.1003324

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© 2013 Xie et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Expression levels of four predicted antimicrobial genes in adult atf-7(gf) and atf-7(lf) mutants. B. Expression levels of the predicted antimicrobial genes in adult tir-1(lf), tir-1(yz68gf), two daf-19 alleles and daf-19;tir-1(yz68gf) double mutants. The levels of all tested genes were reduced in both daf-19 alleles and tir-1(lf) alleles. daf-19(lf) diminished the enhanced expression of the antimicrobial genes in tir-1(yz68gf) mutants. For each gene, the expression level in WT is defined as 1, and that of mutants is relative to WT. Experiments were carried out in triplicates. Results are representative of two independent experiments. Analysis of WT and indicated mutants at the L4 stage showed comparable results. Statistics between WT and mutants is marked on the top of each bar, and that between two indicated groups is marked on the top of lines, ** p<0.01, *** p<0.001.