Table 2. Patients Characteristics of aGVHD+ and aGVHD- groups in kinetic study.
aGVHD+ group | aGVHD- group | ||
No. of patients (male/female) | 16(9/7) | 15(9/6) | P Value |
Age of recipients: median (range),years | 25(17–45) | 26(16–43) | N.S |
Infused MNC (x108/kg): median (range) | 8.1(4.2–12.1) | 7.9(4.7–11.2) | N.S |
All CD3+ T cells | 1.8(0.8–5.2) | 1.7(0.9–4.9) | N.S |
CD4+ T cells | 1.0(0.4–2.9) | 1.0(0.5–2.5) | N.S |
CD8+ T cells | 0.8(0.3–2.5) | 0.7(0.3–2.3) | N.S |
Donor match, no: | |||
Mismatched, related | 11 | 9 | N.S |
Matched, sibling | 5 | 6 | N.S |
CP value (ng/ml): median(SD) | |||
Day -9 | 338 (116.58) | 343(69.01) | N.S |
Day -1 | 550(91.275) | 496(57.14) | N.S |
Day+7 | 650(124.93) | 549(37.92) | 0.001 |
Day+14 | 879(244.76) | 546(63.18) | <0.001 |
Day+21 | 935(242.11) | 483(87.19) | <0.001 |
Day+28 | 668(195.95) | 523(106.46) | 0.001 |
Day+56 | 714(218.50) | 544(154.34) | 0.003 |
Day+90 | 502(68.34) | 498(111.45) | N.S |
Abbreviations: NS, Not Statistically Significant. SD: Standard Deviation.