Table 4. Risk estimates using logistic regression model for three SNPs in TSPAN18.
All (n = 2,115) | All (n = 2,115) | Matched† (n = 1,804) | |||||
SNP | Risk Allele | OR (95%CI) | Punadj ζ | OR (95%CI) | P adj * | OR (95%CI) | P adj * |
rs11038167 | A | 1.026 (0.91–1.156) | 0.6774 | 1.032 (0.9137–1.165) | 0.6147 | 1.04 (0.9118–1.186) | 0.5595 |
rs11038172 | A | 1.072 (0.9502–1.209) | 0.2588 | 1.071 (0.948–1.21) | 0.2696 | 1.083 (0.9487–1.236) | 0.2384 |
rs835784 | A | 1.208 (1.059–1.379) | 0.005034 | 1.197 (1.047–1.369) | 0.008426 | 1.194 (1.033–1.381) | 0.0165 |
Sex- and age- (±2 year-old) matched dataset.
P unadj, un-adjusted p-values in the logistic regression model.
P adj, p-values of the risk allele in the logistic regression model, adjusted by sex and age.