Table 4. Plasma acylcarnitine metabolites in 12 days old TK2^+/+ and TK2^−/− mice.

Acylcarnitines	Carnitine	TK2+/+	TK2−/−	t-test
		[µM]	[µM]	p-value
Short-Chain
	Acetyl (C2)	15.3±2.8	23.5±7.1	0.340
	Propionyl (C3)	0.131±0.013	0.057±0.011	0.012
	Butyryl (C4)	0.539±0.114	0.241±0.033	0.066
	Methylmalonoyl (C4-DC)	0.0257±0.0079	0.0133±0.0017	0.200
	Tiglyl (C5∶1)	0.0007±0.0007	0.0037±0.0023	0.284
	Isovaleryl (C5)	0.0410±0.0410	0.0317±0.0317	0.866
Medium-chain
	Hexanoyl (C6)	0.0853±0.0354	0.0457±0.0122	0.349
	Octanoyl (C8)	0.0350±0.0055	0.0207±0.0003	0.060
	Decenoyl (C10∶1)	0.0013±0.0013	0.0017±0.0017	0.883
	Decanoyl (C10)	0.0470±0.0145	0.0243±0.0038	0.206
	Dodecenoyl (C12∶1)	0.0127±0.0009	0.0613±0.0473	0.362
	Lauryl (C12)	0.0840±0.0405	0.0683±0.0259	0.761
Long-chain
	Myristoleyl (C14∶1)	0.0377±0.0182	0.0750±0.0285	0.331
	Myristoyl (C14)	0.234±0.009	0.418±0.023	0.002
	3-OH myristoyl (C14-OH)	0.0090±0.0015	0.0163±0.0007	0.012
	Palmitoleyl (C16∶1)	0.034±0.010	0.115±0.008	0.004
	3-OH palmitoleyl (C16∶1-OH)	0.0010±0.0010	0.0093±0.0047	0.156
	Palmitoyl (C16)	0.524±0.016	1.433±0.106	0.001
	3-OH palmitoyl (C16-OH)	0.0030±0.0020	0.0193±0.0033	0.013
	Octadecdienoyl (C18∶2)	0.0563±0.0274	0.1097±0.0452	0.370
	3-OH linoleyl (C18∶2-OH)	0	0.001±0.001	0.374
	Octadecenoyl (C18∶1)	0.149±0.033	0.401±0.032	0.005
	3-OH oleyl (C18∶1-OH)	0.0017±0.0017	0.0123±0.0030	0.035
	3-OH stearoyl (C18-OH)	0.0047±0.0047	0.0127±0.0127	0.585
	Steaoryl (C18)	0.0567±0.0119	0.1267±0.0058	0.006

For each time point data from three different mice have been used (n = 3) and are presented as mean ± SEM. Chains highlighted in bold are significantly different (comparisons were made with two-tailed unpaired Student’s t-test) between TK2^+/+ and TK2^−/− mice and exhibit at least p≤0.05.