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. 2013 Mar 7;8(3):e57302. doi: 10.1371/journal.pone.0057302

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© 2013 Chakrabarti et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Microtubule stabilizing and destabilizing compounds exert contrasting effects on their target. Panel A shows P. falciparum without any drug treatment after 24 hours. Panel B shows parasites 24 hours after treated with 500 nM paclitaxel. Images in panel C represents parasites treated with 100 nM vinblastine, after 24 hours. Molar concentration of the drugs was chosen on the basis of published IC₅₀.