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| A. Curcumin (diketo) interacting residues Rank 1 | B. Colchicine interacting residues Rank 1 | ||
| Alpha tubulin | Beta tubulin | Alpha Tubulin | Beta Tubulin |
| Met1 | Leu246 | Met1 | Asn256 |
| Arg2 | Asn256 | Arg2 | Asp327 |
| Lys164 | Asp327 | Thr130 | Met330 |
| Ser165 | Pro346 | Gly131 | Gln334 |
| Asp251 | His347 | Leu132 | His347 |
| Val252 | Thr349 | Gln133 | Thr349 |
| Thr253 | Lys350 | Asp251 | Lys350 |
| Ser351 | Val252 | Ser351 | |
| Thr253 | |||
