Table 3. In vitro activity of sera obtained from blood and homogenates of liver and spleen of mice treated for Salmonella enterica 74.
Group | Treatment | CFU/mlb | ||
Sera | Homogenate | |||
Heart blood | Liver | Spleen | ||
Control | 0.1 ml of a sterile saline | 1.8×108 to 5.9×108 | 6.5×108 to 9.2×108 | 1.6×108 to 8.7×108 |
I | 200 µg of Racemic form | 9.0×104 to 6.6×105 | 2.8×103 to 3.8×104 | 2.5×103 to 4.8×104 |
II | 200 µg of (+) form | 3.6×104 to 9.6×105 | 2.2×104 to 5.0×105 | 7.8×103 to 2.8×105 |
III | 200 µg of (−) form | 1.0×103 to 8.0×105 | 2.0×103 to 4.7×104 | 1.8×103 to 5.7×104 |
Mice received a challenge of 0.95×109 colony-forming units of S. enterica NCTC 74 in 0.5 ml of brain-heart infusion medium.
p<0.001 vs. controls (‘t’ test).