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. 2013 Mar 7;8(3):e57897. doi: 10.1371/journal.pone.0057897

Table 1. Biodistribution of 18F-CML in different organs of ICR mice.

Organ/Uptake Intravenous administration (%ID) Intragastric administration (%ID)
5 min 60 min 120 min 5 min 60 min 120 min
Brain 3.04±0.02 0.38±0.01 0.07±0.00 1.04±0.02 0.31±0.03 0.02±0.01
Intestines 1.02±0.05 2.35±0.01 0.5±0.00 9.91±1.36 52.29±8.71 48.32±5.2
Stomach 0.35±0.02 0.02±0.01 0.01±0.00 76.85±7.01 29.73±3.91 17.87±2.1
Bladder 26.50±1.70 41.28±3.50 72.30±5.20 5.20±1.68 12.21±1.62 29.59±3.7
Lungs 1.65±0.05 1.12±0.02 0.25±0.00 0.35±0.19 0.51±0.11 0.23±0.05
Liver 17.28±2.04 9.72±1.62 3.28±0.05 1.17±0.45 1.0±0.12 0.29±0.05
Pancreas 0.9±0.04 0.01±0.0 0.00±0.02 0.2±0.01 0.32±0.02 0.05±0.00
Muscles 8.02±0.82 5.17±1.12 3.02±0.82 1.76±0.53 2.16±1.82 1.11±1.78
Kidneys 29.30±2.05 35.6±4.06 18.1±2.65 2.20±0.95 3.31±1.91 2.1±0.29
Heart 11.15±0.05 5.05±0.01 1.03±0.00 1.05±0.25 0.75±0.52 0.29±0.59

Radioactivity accumulation was expressed as the percentage of the injected dose per whole tissue (% ID) after a single intravenous injection or a single intragastric administration of 2 MBq of 18F-CML in 0.5 mL of saline with 2% ethanol at 3 different time points (n = 3/group, mean ± SD).