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Rheology studies showing the effect of DNA, histones, and DNA-histone on the critical shear stress needed to disassemble fibrin. Curves are shown for pure fibrin (red), fibrin containing 50 μg/ml DNA (green), and 100 μg/ml DNA (magenta). The addition of histones leads to increased clot stability under sheer stress shown in the presence of 300 μg/ml histone (blue) and 300 μg/ml histone + 100 μg/ml DNA (black). Pa, pascals.
