Skip to main content
. 2013 Jan 24;288(10):6991–6997. doi: 10.1074/jbc.M112.439968

FIGURE 2.

FIGURE 2.

A, agonists used in this study. B, illustration of amide-to-ester mutation. Introduction of an α-hydroxy acid in place of an amino acid eliminates the hydrogen bond donor (backbone NH) of the i residue and attenuates the hydrogen bond-accepting ability of the i−1 carbonyl. The attenuated hydrogen bond is represented by dashed lines.