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Serum FGF23 and phosphorus levels. Serum FGF23 and phosphorus levels of 3-month-old WT, Dmp1 KO, and Dmp1 KO/DSPP Tg mice are shown. The Dmp1 KO mice had significantly elevated FGF23 and reduced phosphorus levels compared with WT mice. The transgenic expression of DSPP failed to restore the serum FGF23 and phosphorus levels to the ranges comparable with those of WT mice. All values are mean ± S.D. n = 3 in each group.
