Table 4.

Comparison of eIPSCs in R6/2 WT and CAR based on 20 Hz test according to small RRP (N < 7) and large RRP (N≥ 7)

	WT			CAR
Property	Mean	±SEM	n	Mean	±SEM	n	p value	Test
Small N (SON–SON?)
Mean eIPSC amplitude (pA)	84.04	9.18	28	81.96	7.48	22	0.8665	Student's unpaired t test
PPR (eEPSC2/eEPSC1)	0.74	0.03	28	0.84	0.04	22	0.0823	Student's unpaired t test
Pves (mean eIPSC/cumulative eIPSC at time 0)	0.45	0.04	28	0.33	0.03	22	0.0503	Student's unpaired t test
Large N (interneuron–SON?)
Mean eIPSC amplitude (pA)	205.72	20.30	29	145.23	11.37	32	0.0099	Student's unpaired t test
PPR (eEPSC2/eEPSC1)	0.71	0.02	29	0.82	0.03	32	0.0052	Student's unpaired t test
Pves (mean eIPSC/cumulative eIPSC at time 0)	0.32	0.02	29	0.23	0.02	32	0.0043	Student's unpaired t test

The tested connections were divided according to their RRP size. Note that connections with small RRP (N < 7) and connections with large RRP (N≥ 7) were differentially affected by HD. For abbreviations see list on Introduction page.