Figure 7.

Significantly diminished circulating levels of multiple tissue damage markers in Fibγ^Δ5 mice following intravenous S. aureus infection. The levels of cardiac troponin I (A), creatine kinase (B), lactate dehydrogenase (C), and AST (D) were determined in plasma from wild-type and Fibγ^Δ5 mice that were unchallenged (N = 6 per genotype) or administered and intravenous infection of ∼2.5 × 10⁸ CFUs of S. aureus for 24 hours or 48 hours (N = 8 per genotype). The data are represented as the mean ± standard error of the mean and analyzed using the Student t test.