Table 1.
Blood cell parameters in wild-type and FibγΔ5 mice 24 h after intravenous infection with 2.1 × 108 CFUs S. aureus
| Parameter | Unchallenged | S. aureus | ||
|---|---|---|---|---|
| Wild-type N = 5 | FibγΔ5 N = 5 | Wild-type N = 7 | FibγΔ5 N = 5 | |
| WBC (×109/L) | 3.5 ± 1.1 | 2.1 ± 0.4 | 0.4 ± 0.2* | 0.7 ± 0.2* |
| RBC (×1012/L) | 8.3 ± 0.03 | 7.6 ± 0.4 | 6.8 ± 2.6 | 9.2 ± 0.8 |
| Hemoglobin (g/dL) | 13.1 ± 0.2 | 11.6 ± 0.6 | 11.8 ± 1.4 | 13.1 ± 2.2 |
| Hematocrit (%) | 40.8 ± 0.8 | 37.3 ± 1.5 | 35.8 ± 12.5 | 45.6 ± 2.8 |
| MCV (fL) | 49.1 ± 0.8 | 49.3 ± 0.4 | 52.3 ± 7.3 | 49.8 ± 4.3 |
| RDW (%) | 15.6 ± 0.3 | 16.8 ± 0.6 | 19.1 ± 4.1 | 15.6 ± 0.4 |
| Platelets (×109/L) | 666 ± 42 | 576 ± 113 | 228 ± 77* | 208 ± 66* |
MCV, mean corpuscular volume (in femtoliters); RBC, red blood cells; RDW, red cell distrobution width; WBC, white blood cells.
*
P < 0.05 by Student t test relative to values in unchallenged mice.