Table 1.
Characteristic | Result by treatment assignment |
P value | ||
---|---|---|---|---|
AS | QN+PQ | DHA-PP+PQ | ||
No. (%) of subjects | 41 (35.3) | 39 (33.6) | 36 (31.0) | 0.78 |
Age (yr) | ||||
Mean | 27.7 | 27.1 | 27.8 | 0.89 |
Range | 21.5–38.8 | 22.1–31.5 | 23.6–42.1 | |
Wt (kg) | ||||
Mean | 66.5 | 65.4 | 65.0 | 0.90 |
Range | 52–90 | 52–90 | 55–78 | |
Mean tympanic temp (°C) | 36.7 | 36.7 | 36.9 | 0.67 |
No. (%) of febrile patients | 7 (17.1) | 7 (18.0) | 12 (33.3) | 0.17 |
Parasite count (no. of parasites/μl blood) | ||||
Median | 1,408 | 1,304 | 2,264 | 0.83 |
Range | 32–15,248 | 32–8,560 | 48–10,112 | |
Mean hemoglobin concn (g/dl) | 14.2 | 14.0 | 13.5 | 0.06 |
Mean blood glucose concn (mg/dl) | 108 | 107 | 110 | 0.82 |
Mean total bilirubin level (mg/dl) | 1.95 | 1.69 | 1.97 | 0.23 |
Mean platelet count (no. of platelets [103]/ml) | 167 | 162 | 156 | 0.64 |
Mean white blood cell count (no. of cells/μl) | 7,700 | 7,500 | 7,700 | 0.83 |