Table 2.
Single-dose pharmacokinetics of vancomycin in infected micea
| Dose (mg/kg) | Cmax (mg/liter) | t1/2 (min) | AUC (mg · h/liter) |
|---|---|---|---|
| 25 | 34.1 | 26.5 | 27.6 |
| 50 | 57.5 | 29.0 | 45.0 |
| 100 | 72.7 | 34.3 | 85.8 |
| 200 | 112 | 42.0 | 165 |
| 800 | 252 | 52.0 | 680 |
a
t1/2, half-life.
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