Table 3.
Mutation type and rpoB nucleotide changed | RpoB amino acid substitution | Mutation frequency (%) (n = 42) |
---|---|---|
Transversions | ||
1564 CAG → AAG | 522 Gln → Lysa | 7 |
1565 CAG → CTG | 522 Gln → Leua | 10 |
1573 GAC → TAC | 525 Asp → Tyrb | 5 |
1574 GAC → GTC | 525 Asp → Valc | 5 |
1603 CAT → GAT | 535 His → Aspa | 2 |
1604 CAT → CTT | 535 His → Leub | 12 |
1619 TCT → TAT | 540 Ser → Tyrb | 12 |
1741 ATC → TTC | 581 Ile → Phea,b | 14 |
Total | 67 | |
Transitions | ||
1565 CAG → CGG | 522 Gln → Arga,b | 12 |
1603 CAT → TAT | 535 His → Tyra | 2 |
1619 TCT → TTT | 540 Ser → Phea | 7 |
1625 CTT → CCT | 542 Leu → Proa,b | 10 |
1696 CGT → TGT | 566 Arg → Cysa,c | 2 |
Total | 33 |
Novel Acinetobacter substitution.
The mutation was also found in an A. baumannii ATCC 17978 dinB::Km strain.
The mutation was unique to A. baumannii ATCC 17978 dinB::Km strain.
Boldface and underscoring indicate the nucleotide changes.