Table 3.
Species | Antifungal agent (no. of isolates tested) | MIC (μg/ml) |
||
---|---|---|---|---|
Range | 50% | 90% | ||
C. albicans | Amphotericin B (124) | 0.002–0.50 | 0.125 | 0.25 |
Fluconazole (124) | 0.023–1.0 | 0.19 | 0.5 | |
Itraconazole (116) | 0.004–0.32 | 0.032 | 0.125 | |
Voriconazole (64) | 0.002–0.38 | 0.008 | 0.016 | |
Caspofungin (41) | 0.023–0.38 | 0.19 | 0.25 | |
C. glabrata | Amphotericin B (36) | 0.002–1.0 | 0.38 | 0.75 |
Fluconazole (36) | 0.023–48 | 1.5 | 16 | |
Itraconazole (35) | 0.064–32 | 0.75 | 32 | |
Voriconazole (22) | 0.002–1.5 | 0.064 | 0.75 | |
Caspofungin (14) | 0.064–0.38 | 0.19 | 0.38 | |
C. tropicalis | Amphotericin B (28) | 0.002–0.75 | 0.125 | 0.50 |
Fluconazole (28) | 0.125–8 | 0.38 | 1.0 | |
Itraconazole (27) | 0.003–1.5 | 0.016 | 0.064 | |
Voriconazole (16) | 0.006–0.5 | 0.032 | 0.094 | |
Caspofungin (7) | 0.064–0.75 | 0.19 | 0.75 | |
C. dubliniensis | Amphotericin B (12) | 0.012–0.38 | 0.064 | 0.125 |
Fluconazole (12) | 0.047–2 | 0.125 | 0.38 | |
Itraconazole (12) | 0.003–0.50 | 0.016 | 0.38 | |
Voriconazole (6) | 0.002–0.012 | 0.006 | 0.012 | |
Caspofungin (3) | 0.25–0.50 | 0.38 | 0.50 | |
C. parapsilosis | Amphotericin B (11) | 0.125–0.38 | 0.19 | 0.25 |
Fluconazole (11) | 0.047–1.5 | 0.25 | 1.0 | |
Itraconazole (11) | 0.006–0.094 | 0.023 | 0.064 | |
Voriconazole (5) | 0.003–0.016 | 0.004 | 0.016 | |
Caspofungin (5) | 1.0–2 | 1.5 | 2 |