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. 2013 Mar;51(3):841–848. doi: 10.1128/JCM.02566-12

Table 3.

In vitro susceptibilities of Candida bloodstream isolates to five antifungals, Iceland, 2000 to 2011

Species Antifungal agent (no. of isolates tested) MIC (μg/ml)
Range 50% 90%
C. albicans Amphotericin B (124) 0.002–0.50 0.125 0.25
Fluconazole (124) 0.023–1.0 0.19 0.5
Itraconazole (116) 0.004–0.32 0.032 0.125
Voriconazole (64) 0.002–0.38 0.008 0.016
Caspofungin (41) 0.023–0.38 0.19 0.25
C. glabrata Amphotericin B (36) 0.002–1.0 0.38 0.75
Fluconazole (36) 0.023–48 1.5 16
Itraconazole (35) 0.064–32 0.75 32
Voriconazole (22) 0.002–1.5 0.064 0.75
Caspofungin (14) 0.064–0.38 0.19 0.38
C. tropicalis Amphotericin B (28) 0.002–0.75 0.125 0.50
Fluconazole (28) 0.125–8 0.38 1.0
Itraconazole (27) 0.003–1.5 0.016 0.064
Voriconazole (16) 0.006–0.5 0.032 0.094
Caspofungin (7) 0.064–0.75 0.19 0.75
C. dubliniensis Amphotericin B (12) 0.012–0.38 0.064 0.125
Fluconazole (12) 0.047–2 0.125 0.38
Itraconazole (12) 0.003–0.50 0.016 0.38
Voriconazole (6) 0.002–0.012 0.006 0.012
Caspofungin (3) 0.25–0.50 0.38 0.50
C. parapsilosis Amphotericin B (11) 0.125–0.38 0.19 0.25
Fluconazole (11) 0.047–1.5 0.25 1.0
Itraconazole (11) 0.006–0.094 0.023 0.064
Voriconazole (5) 0.003–0.016 0.004 0.016
Caspofungin (5) 1.0–2 1.5 2