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Soluble polysaccharides inhibit infection of Vero cells by wild-type EBOV. EBOV was incubated with different concentrations of soluble heparin or carrageenan and then added to a monolayer of Vero cells for 2 h. Virus was removed, and the cells were cultured for 8 days in the presence of the compounds. Titers were determined by plaque assay. Results are expressed as PFU/ml and represent the means ± SD for duplicate wells.
