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. 2013 Mar;87(6):3571–3577. doi: 10.1128/JVI.01292-12

Fig 3.

Fig 3

Determination of effects of antibodies 65C6 and 100F4 on virus neutralization, attachment, postattachment, and fusion. (A) Neutralization activity against H5N1 pseudotype A/Shenzhen/406H/06 by indicated concentrations of antibodies 65C6, 100F4, AVIg03, F10, and PG16. The neutralization activity was calculated as follows: relative luciferase activity (RLA) of pseudotype with a given concentration of an antibody/RLA of pseudotype alone without antibodies. (B) Effects of indicated concentrations of antibodies 65C6, 100F4, AVIg03, F10, and PG16 on binding of H5N1 pseudotype A/Shenzhen/406H/06 to MDCK cells compared to binding of pseudotype alone (without antibodies). (C) Effects of indicated concentrations of antibodies 65C6, 100F4, AVIg03, F10, and PG16 on postattachment entry of H5N1 pseudotype A/Shenzhen/406H/06 into MDCK cells compared to entry of pseudotype alone (without antibodies). (D) Effects of antibodies 65C6, 100F4, AVIg03, F10, and PG16 on pH 5.0-triggered, HA-mediated cell-cell fusion among influenza H5 HA-transduced HeLa cells. (E) Mean and standard deviation of fusion percentages in each image in panel D. The fusion percentages were calculated as described in the text.