Fig 8.

CD22 expression regulates production of specific chemokines early in the WNV-infected dLNs. (A to D) Mice were inoculated and dLNs were harvested at indicated time points p.i. Relative expression levels of the indicated genes were quantified and graphed as fold change using TaqMan (A, B, and C) or Sybr green (D) as described in Materials and Methods. Data show one representative of three independent experiments with at least two mice per group per time point. (E) Mice were inoculated and serum samples taken at the indicated time points. Type I IFN production was quantified from serum samples using a standard bioassay. Data are represented as international units (IU) per ml of serum. Data show one representative of two independent experiments with three mice per group per time point. Statistics were performed using Student's t test. *, P < 0.05; **, P < 0.01. n.s., not significant.