[Table/Fig-3]:
Region | Controls (n=10) | GBM (n=27) | Metastases (n=11) | Gbm vs. Control | Metastases vs. Control | GBM vs. Metastases | |
---|---|---|---|---|---|---|---|
Rostrum | FA | 0.53 ± 0.05 | 0.43 ± 0.11 | 0.42 ± 0.10 | 0.001 | 0.007 | 0.699 |
MD | 0.70 ± 0.08 | 0.84 ± 0.22 | 0.89 ± 0.23 | 0.007 | 0.024 | 0.543 | |
Genu | FA | 0.55 ± 0.02 | 0.50 ± 0.05 | 0.50 ± 0.05 | <0.001 | 0.004 | 0.601 |
MD | 0.61 ± 0.05 | 0.67 ± 0.08 | 0.69 ± 0.09 | 0.028 | 0.022 | 0.583 | |
Rostral body | FA | 0.49 ± 0.04 | 0.40 ± 0.07 | 0.41 ± 0.08 | <0.001 | 0.008 | 0.957 |
MD | 0.67 ± 0.08 | 0.80 ± 0.15 | 0.82 ± 0.16 | 0.014 | 0.015 | 0.681 | |
Anterior midbody | FA | 0.49 ± 0.05 | 0.38 ± 0.07 | 0.39 ± 0.09 | <0.001 | 0.005 | 0.614 |
MD | 0.68 ± 0.08 | 0.86 ± 0.17 | 0.85 ± 0.16 | <0.001 | 0.009 | 0.75 | |
Posterior midbody | FA | 0.49 ± 0.04 | 0.39 ± 0.05 | 0.40 ± 0.07 | <0.001 | 0.005 | 0.416 |
MD | 0.72 ± 0.09 | 0.89 ± 0.13 | 0.85 ± 0.15 | <0.001 | 0.025 | 0.42 | |
Isthmus | FA | 0.47 ± 0.05 | 0.39 ± 0.07 | 0.39 ± 0.08 | 0.003 | 0.015 | 0.884 |
MD | 0.79 ± 0.11 | 0.90 ± 0.15 | 0.89 ± 0.16 | 0.041 | 0.116 | 0.799 | |
Splenium | FA | 0.58 ± 0.04 | 0.53 ± 0.05 | 0.52 ± 0.05 | 0.004 | 0.005 | 0.413 |
MD | 0.64 ± 0.05 | 0.68 ± 0.07 | 0.70 ± 0.07 | 0.083 | 0.032 | 0.466 |
FA = fractional anisotropy; MD = mean diffusivity; GBM = glioblastoma multiforme; CC = corpus callosum; SD = standard deviation. p < 0.05 was statistically significant.