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Immunohistochemistry for detection of PRRSV antigens in the lung. (A) PRRSV antigens (arrows) were detected at 21 dpc in macrophages in severely thickened alveolar septa of lungs from pigs which received the PRRSV vaccine followed by dual challenge (group 4). (B) PRRSV antigens (arrow) were occasionally detected at 21 dpc in macrophages in mildly thickened alveolar septa of lungs from pigs which received the PRRSV vaccine followed by PRRSV challenge (group 3).
