Fig 2.

Overview of interaction PRRs. Color indicates type of interaction in at least 7 of 10 of the healthy volunteers. Data represent results of an ELISA on culture supernatants after 24 h of stimulation at 37°C with combinations of ligands as specified in Table 1. *, P < 0.05 (Wilcoxon matched-pair test, comparison of cytokine production upon stimulation with both ligands with sum of cytokine production values upon stimulation with each of the ligands separately). Red, synergistic effect; green, no effect/additive effect; blue, inhibitory effect; white, variable effect; black, experiment not performed.