Oxidative stress profile. A, Myocardial protein oxidation showing significantly increased protein oxidation in oral hypercaloric/hypercholesterolemic diet plus 1.5 mg/kg atorvastatin daily (OHCS) compared with oral hypercaloric/hypercholesterolemic diet (OHC) groups. B, Serum lipid peroxidation. Significantly increased lipid peroxidation was seen in OHCS group compared with OHC group. C, Western blot analysis of oxidative stress protein expression showing no difference in expression of proteins involved in oxidative stress. *P<.05. AMPK, Adenosine monophosphate kinase; eNOS, endothelial nitric oxide synthase; pAkt, phosphorylated Akt; pAMPK, phosphorylated AMPK; peNOS, phosphorylated eNOS; VEGF, vascular endothelial growth factor; VEGFR2, VEGF receptor 2.