Table 3.

Performance of the CNV detection methods in localizing the variants’ boundaries in genomes from 15 different cancer cell lines

Boundary mismatch	Entropy-based method			Circular binary segmentation	CNA-HMMer	CRF-CNV
	Sensitivity	Specificity	F-measure	F-measure	F-measure	F-measure
0	0.62	0.67	0.65	0.33	0.87	0.63
1	0.74	0.80	0.77	0.50	0.94	0.91
2	0.81	0.87	0.84	0.51	0.94	0.94
3	0.88	0.95	0.91	0.51	0.94	0.96
4	0.93	1.0	0.96	0.51	0.94	0.96