Table 1.
Cis regulatory elements in P. aeruginosa transcriptional regulation
| Transcription factor | Cis regulatory element | Major virulence phenotype regulated | Reference |
|---|---|---|---|
| AlgR | ACCGTTCGTC | Alginate production, biofilm formation, T3SS | (43) |
| AlgZ | GGCCATTACCAGCC | Alginate production | (44) |
| Anr | TTGATN4ATCAA | Anaerobic regulator of QS | (45) |
| ArgR | TGTCGCN8AA | Carbon and nitrogen catabolism | (46) |
| ExsA | TNAAAANA | T3SS | (47) |
| FleQ | Box 1: CGCCTAAAAATTGACAGTT | Motility, biofilm formation | (48) |
| Box 2: CATTAGATTGACGTTAATC | |||
| Fur | GATAATGATAATCATTATC | Iron uptake | (49) |
| LasR (las box) | NHCTRNSNNDHNDKNNAGNB | QS | (50) |
| MexT | ATCAN5GTCGATN4ACYAT | Antibiotic resistance, T3SS, QS | (51) |
| MvfR | TTCGGACTCCGAA | QS | (52) |
| PsrA | G/CAAACN2-4GTTTG/C | Stress regulon (RpoS), T3SS | (53) |
| RcsBa | TTA-GAAACGTCCTAAA | Fimbriae | (54) |
| RhlR (lux box) | CCTGTGAAT/ATCC/TGGT/CAGTT | QS | (55) |
| Vfr | AATTGACTAATCGTTCACATTTG | QS | (56) |
| VqsR | TCGCCN8GGCGA | QS | (57) |
H = C/T/A; R = A/G; S = C/G; D = G/A/T; K = G/T; B = C/G/T; N = A/C/G/T.
aRcsB is found only in P. aeruginosa PA14, not in P. aeruginosa PAO1.