Table 4.
As estimated by latent class analysis of all available subject data, test sensitivity, and specificity of Kato-Katz microscopy of a single stool, POC-CCA testing of a single urine, and of PCR testing of a single stool in the Schistosoma mansoni-endemic areas included in this study*
| Assay | Criterion | Countries | |||||
|---|---|---|---|---|---|---|---|
| Cameroon | Ethiopia | Côte d'Ivoire | Kenya | Uganda | Overall | ||
| Kato-Katz | Sensitivity | 64% | 59% | 77% | 44% | 61% | 62% |
| POC-CCA | Sensitivity | 87% | 92% | 78% | 86% | 89% | 86% |
| Specificity | 74% | 94% | 92% | 70% | 56% | 72% | |
| PCR | Sensitivity | 69% | |||||
| Specificity | 91% | ||||||
*
Results are listed for each participating study country and for all countries combined.
POC-CCA = point-of-care assays for parasite circulating cathodic antigen; PCR = polymerase chain reaction.