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. 2013 Feb 25;8:835–843. doi: 10.2147/IJN.S40238

Figure 4.

Figure 4

Cytokine production by the splenocytes stimulated with CFP-10. Splenocytes collected from each group of mice 1 week after the final immunization were stimulated with CFP-10 (5 μg/mL). Con A (5 μg/mL) and buffer were used as controls. (A) IFN-γ; (B) IL-2; (C) TNF; (D) IL-5; (E) IL-10.

Notes: The concentrations of cytokines in the splenocyte culture supernatant were determined by ELISAs. The data are presented as mean ± standard deviation. Statistical significance between groups is indicated as ***P < 0.001, **P < 0.05.

Abbreviations: IFN-V, interferon-gamma; IL-2, interleukin-2; TNF, tumor necrosis factor; IL-5, interleukin-5; IL-10, interleukin-10; CF, culture filtrate of Mtb; G1, buffer-immunized group; G2, CFP-10-immunized group; G3, HBc-VLP-immunized group; G4, HBc + CFP-10-immunized group; G5, FVLP-immunized group; Con A, concanavalin A; CF, culture filtrate of Mtb.