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Summary of Hilde Mangold’s dorsal lip transplantation experiment (Spemann and Mangold, 1924). A graft of dorsal lip tissue from a pigmented embryo (a) placed in the blastocoele of an albino embryo (b) gives rise to conjoined embryos (d). Organs of the ‘secondary embryo’ contain a mix of pigmented and nonpigmented tissues, (c) indicating that the graft exerted an “organizing” effect on the host. Figure from Holtfreter and Hamburger, 1955.
