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. 2013 Mar 8;8(3):e58480. doi: 10.1371/journal.pone.0058480

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© 2013 Castro-Sesquen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Hematoxylin-eosin stain: A). Amastigote nests (arrows) and tubular necrosis, 25 dpi (500x). B). Focal and mild periglomerular and interstitial inflammation (arrows), 25 dpi (100x). C). Glomerulus of non-infected guinea pig. Note the number of nucleus (1 to 3) in the mesangium (1000x). D). Mesangial hypercellularity and congestion (arrows), 365 dpi (400x). E). Dilatation of proximal tubules (arrows) and periglomerular inflammation, 40 dpi, (200x). Masson’s Trichromic stain: F). Kidney tissue of non-infected guinea pig (400x). G). Mild increase in interstitial collagen, 365 dpi (400x). H). Moderate increase in interstitial collagen and tubular atrophy, 25 dpi (200x).