Figure 7. Effect of iron repletion-depletion on virus titer.

Virus titers, assayed by TCID₅₀ method and reported as Log TCID₅₀/ml, in iron deplete-replete MDBK cells exposed to 0.01, 1, 100 pg/ml of TCDD at 48 h post-BHV-1 infection (MOI of 1), as indicated in the legends. In iron depletion – repletion experiments, MDBK cells were treated with 100 μM desferrioxamine (DFO) or with 50 μg/ml ferric ammonium citrate (FAC).